Please describe the problem:
With Ubuntu 8.10 (latest 2.6.27-7-generic kernel) and GNome 2.24.1 mouse is configured to be 'left handed' via the System -> Preferences -> Mouse.  I switch to another computer on my KVM, do some work and then switch back to ubuntu computer.  Mouse preferences have now been reset to right handed.  

Temporary fix:  Reset the preferences via System->Preferences->Mouse panel again.  

This is a new issue since Ubuntu 8.04 with the latest kernel for it.  The mouse is a MSFT Optical USB mouse connected to an IOGear KVM that supports USB Keyboard/Mouse.

Steps to reproduce:
1. Install Ubuntu 8.10 w/GNome 2.24.1, connect to computer via KVM with USB mouse & keyboard.
2. Switch to another computer on the KVM box
3. Switch back to ubuntu box; mouse preferences have been reset to right handed


Actual results:
Mouse settings are gone and reset to right-handed.

Expected results:
Mouse settings stay at left-handed configuration

Does this happen every time?
Yes

Other information:
As mentioned in the description, this was not an issue on the 8.04 install.  I upgraded to 8.10 and the problem has appeared.  No luck getting any suggestions on ubuntu forums.  Am willing to experiment, need guidance on the 'how' though.