Create a 2x2 image, the upper left and lower right pixels black, the upper right and lower left pixels white.  Use the "Scale image..." dialogue to resize the image to 16x16 (it doesn't matter if this is by pixel count or by percentage) using no interpolation.  The output is almost entirely black; only the leftmost and uppermost pixels, not including the upperleftmost pixel, are white.  The results look different with interpolation, but are still wrong.